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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Guanidines
drug:
Pyruvic Acid
Research Papers that Mention the Interaction
“For L-lactate dehydrogenases (LDH's), the interaction of the guanidinium group of their Arg 171 residue with the carboxylate group of an alpha-keto acid is of primary importance in orienting the substrate productively at the active site.”
On the effects of replacing the carboxylate-binding arginine-171 by hydrophobic tyrosine or tryptophan residues in the L-lactate dehydrogenase from Bacillus stearothermophilus.
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