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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Guanethidine
supplement:
Yohimbine
Research Papers that Mention the Interaction
“ Yohimbine failed to counteract the inhibition caused by guanethidine and the increment of the basal release was Ca-independent.”
Biphasic effect of tricyclic antidepressants on the release of norepinephrine from the adrenergic nerves of the rabbit heart“CCK8-induced relaxation in the presence of yohimbine was abolished by pretreatment with guanethidine , 6-hydroxydopamine, celiac ganglionectomy and hexamethonium but not by VIP antiserum or a nitric oxide (NO) inhibitor.”
“ Guanethidine and/or bretylium, the adrenergic neuron blockers, attenuated this action of yohimbine , indicating the participation of neuronal alpha 2-adrenoceptors.”
“This inhibitory response was blocked by the administration of either the adrenolytic agent guanethidine or the alpha 2-adrenoceptor antagonist yohimbine.”
“ Guanethidine pretreatment antagonized the tachycardia and converted the pressor response to yohimbine into a depressor one.”
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