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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Guanethidine
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“Chemical … guanethidine (20 mg/kg body wt) decreased basal and stimulated corticosterone compound B (… without affecting adrenocorticotropic hormone (ACTH) release, abolished the enhanced adrenal sensitivity to ACTH induced by maternal separation in 10-day-old pups, but did … modify adrenal sensitivity following ether stress in 23-day-old pups.”
Chemical sympathectomy and maternal separation affect neonatal stress responses and adrenal sensitivity to ACTH.“On the other hand, reserpine, guanethidine , and alpha-adrenoceptor blocking drugs inhibit the anti-shock effect of ACTH as well as that of oxotremorine and physostigmine.”
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