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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“ Yohimbine (1 mg/kg) produced greater antagonism of the pressor effects of guanabenz and xylazine than did prazosin.”
A comparison of pre- and post-junctional potencies of several alpha-adrenoceptor agonists in the cardiovascular system and anococcygeus muscle of the rat“Idazoxan and yohimbine also fully antagonised the inhibitory effects of guanabenz on electrically-induced contractions of the anococcygeus muscle; idazoxan again was more than ten times more potent than yohimbine in this model.”
“Intracisternal pretreatment with yohimbine inhibited both cardiovascular responses to guanabenz , whereas intravenous pretreatment with yohimbine affected neither.”
“The depressor response to guanabenz was inhibited by intrathecal pretreatment with yohimbine , while this pretreatment did not affect the bradycardic response to guanabenz.”
“The actions of clonidine and guanabenz were also blocked by yohimbine and/or rauwolscine.”
“The action of UK 14,304 and guanabenz was also blocked by idazoxan, rauwolscine and yohimbine but not by L 659,066.”
“Under the same conditions, yohimbine fully prevented the actions of clonidine, xylazine and guanabenz , while tolazoline showed partial antagonism.”
“The alpha 2-agonists clonidine, alpha-methylnorepinephrine and guanabenz also hyperpolarized terminals, causing a change in potential that was reduced by yohimbine and piperoxan.”
“In the tail flick assay, the antinociceptive activity of guanabenz and clonidine was antagonized by yohimbine but not by naloxone or phenoxybenzamine.”
“Phentolamine and yohimbine reversed the twitch-inhibitory effects of guanabenz and clonidine, but naloxone failed to reverse this action.”
“ Guanabenz in concentrations higher than 10(-6) M produced weak contractions which were attenuated by phentolamine or yohimbine.”
“Phentolamine or yohimbine effectively blocked these inhibitory effects of guanabenz.”
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