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Discover Supplement-Drug Interactions

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Possible Interaction: Guanabenz and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

Guanabenz did not affect the cGMP content of purified adrenal glomerulosa cells but inhibited ACTH stimulation of cAMP accumulation.
Guanabenz inhibited aldosterone secretion stimulated by potassium, angiotensin II (AII), and adrenocorticotropic hormone (ACTH), exhibiting IC50 values of 35 microM, 43 microM, and 58 microM for stimulation by 10 mM K+, 1 nM AII, and 10 pM ACTH, respectively.
The American journal of the medical sciences  •  1991  |  View Paper