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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Grapefruit Extract
drug:
Sacubitril
Research Papers that Mention the Interaction
“In conclusion, the current study demonstrated that grapefruit juice decreased SAC hydrolysis, hence delaying its activation to sacubitrilat (active form) in gut lumen.”
A validated RP-HPLC method for the evaluation of the influence of grapefruit juice on liver S9 activation of sacubitril.
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