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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gossypol
drug:
Zoledronic Acid
Research Papers that Mention the Interaction
“Moreover, the combination treatment of 10 microM gossypol and 5 microM zoledronic acid resulted in significant down-regulation (>or= thee-fold) in mRNA levels of some pivotal angiogenic molecules in OVCAR-3 and MDAH-2774 cells as compared to the untreated control.”
Combined gossypol and zoledronic acid treatment results in synergistic induction of cell death and regulates angiogenic molecules in ovarian cancer cells.“Possible synergistic cytotoxic and apoptotic effects of gossypol with zoledronic acid on DU‐145 cells were explored, along with the rationale behind any observed synergism due to the different apoptotic proteins involved.”
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