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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“ NADH was shown to partially protect the enzymes against inactivation by gossypol.”
Enzyme inactivation and inhibition by Gossypol“For the conversion of pyruvate to lactate the IC50 for … the reverse reaction the IC50 is 12 microM. Gossypol … NADH , Ki = 30 microM (Km = 17 microM), and NAD+, Ki = 6 microM (Km = 130 microM), and … = 220 microM (Km = 224 microM), and lactate, Ki = 52 microM (Km = 5.6 mM).”
“The inhibitory effect of gossypol was competitive with respect to NADH , but non-competitive with respect to alpha-ketoglutarate.”
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