“The results suggest that combination of gossypol and misoprostol showed synergistic effect on termination of early pregnancy in mice.”
“When giving misoprostol 200-6400 micrograms.kg-1 bid on day 9 of gestation following administration of gossypol 50 mg.kg-1 qid on day 6-8, the rate of abortion increased as the dose of misoprostol increased, and the ED50 of misoprostol was 397.8 micrograms.kg-1.”