Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Gossypol and Misoprostol

supplement:

Gossypol

Research Papers that Mention the Interaction

The results suggest that combination of gossypol and misoprostol showed synergistic effect on termination of early pregnancy in mice.
When giving misoprostol 200-6400 micrograms.kg-1 bid on day 9 of gestation following administration of gossypol 50 mg.kg-1 qid on day 6-8, the rate of abortion increased as the dose of misoprostol increased, and the ED50 of misoprostol was 397.8 micrograms.kg-1.
Yao xue xue bao = Acta pharmaceutica Sinica  •  1997  |  View Paper