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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gossypol
drug:
Lonidamine
Research Papers that Mention the Interaction
“4) Gossypol enhances the effect of Lonidamine on oxygen consumption.”
“5) It may be concluded that gossypol is very effective in potentiating the effect of Lonidamine.”
“ Lonidamine does not affect state 4 respiration, but in the presence of gossypol , it determines a marked decrease in the rate of oxygen consumption.”
The effect of gossypol and Lonidamine on electron transport in Ehrlich ascites tumor mitochondria.“3) The association of a low concentration of Gossypol with Lonidamine brings about a further inhibition of oxygen consumption.”
“4) It may be concluded that the association of Gossypol and Lonidamine results in a very effective decrease of the energy requirements of cancer cells.”
“Moreover, Lonidamine abolishes the stimulation of glycolysis induced by Gossypol and lowers lactate production to values that are quite similar to those found with Lonidamine alone. (”
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