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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gossypol
Research Papers that Mention the Interaction
“Combination therapy with L‑gossypol and LCD inhibited cell proliferation and induced apoptosis in SW982 HSSCs at a significantly greater level compared with either treatment alone.”
Combination of L-gossypol and low-concentration doxorubicin induces apoptosis in human synovial sarcoma cells.“Our data showed that treatment of Ramos cells with gossypol not only induced cell arrest on the G0/G1 phase, but also augmented apoptosis and growth inhibition induced by etoposide (VP-16), doxorubicin hydrochloride (ADM), vincristine (VCR), and paclitaxel (taxol).”
“Interestingly, gossypol exhibits synergistic activity with chemotherapeutic agents, such as doxorubicin [4].”
Attenuating Effect of Gossypol on Tumor Growth in Systemic Malignancies
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