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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Gossypol and Buthionine Sulfoximine

Research Papers that Mention the Interaction

We report that the (-.)enantiomer of gossypol is a potent and selective inhibitor of GST alpha and GST pi isozymes, and that in combination with buthionine sulfoximine (BSO), causes the enhanced modulation of alkylator resistance in two drug resistant cell lines with increased GST activity.
Cancer letters  •  1991  |  View Paper