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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gossypol
drug:
Bortezomib
Research Papers that Mention the Interaction
“A combination of gossypol with any of the three natural products identified in this study, as well as with bortezomib , a previously reported anti-ZIKV compound, exhibited significant combinatorial inhibitory effects against three ZIKV human strains tested.”
Identification of Novel Natural Products as Effective and Broad-Spectrum Anti-Zika Virus Inhibitors“Concomitant or sequential exposure to …- or minimally toxic concentrations of bortezomib or other proteasome inhibitors and either HA14-1 or gossypol resulted in a striking increase in Bax/Bak conformational change/translocation, cytochrome c release, caspase activation, and synergistic induction of apoptosis in both GC- and ABC-type cells.”
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