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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Selenium
Research Papers that Mention the Interaction
“T administration suppressed the mean serum … about 50% of the value during GnRH … (+/- SE ) vs. 37 +/- 2 micrograms/L; P less than 0.05] and suppressed the mean serum FSH level to … the value during GnRH alone (39 +/- 6 vs. 128 +/- 28 micrograms/L; P less than 0.05).”
Testosterone administration inhibits gonadotropin secretion by an effect directly on the human pituitary.“In controls, GHRH (100 micrograms intravenously [IV]) injection increased GH levels from 2.3 +/- 1.8 (+/- SE ) to 18.5 +/- 2.8 mU/L, P less than .002.”
“There was a marked serum GH rise in acromegalic patients and normal subjects after the first GHRH dose [area under the curve, 2070 +/- 532 (+/- SE ) vs. 1558 +/- 612 ng/min X ml, respectively; P = NS].”
“ GRF (10 nM) rapidly increased the intracellular free calcium concentration ([ Ca2+]i) from a basal level of 234 +/- 17 nM (mean +/- SE ) to a peak value of 480 +/- 61 nM 1 min after stimulation.”
Intracellular calcium concentration and growth hormone secretion in individual somatotropes: effects of growth hormone-releasing factor and somatostatin.“E2 (10(-8) mol/L) exposure for 72 h resulted in a significant increase in LH release when cells were stimulated with GnRH and caused a significant shift to the left of the dose-response curve for GnRH-stimulated LH release [relative potency ratio, 0.33 +/- 0.05 (+/- SE)].”
Estradiol sensitization of cultured human fetal pituitary cells to gonadotropin-releasing hormone.
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