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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Polypeptides
Research Papers that Mention the Interaction
“The polymeric polypeptide carrier is supposed to increase the stability of the GnRH antagonist and to prevent the rapid excretion of the covalently bound peptide molecule.”
Antitumour effect of a gonadotropin-releasing-hormone antagonist (MI-1544) and its conjugate on human breast cancer cells and their xenografts“The polypeptide rather may modulate the responses to factors such as gonadotrop hormone releasing hormone or have more general actions by regulating hormone synthesis or cell differentiation.”
“These results suggest that GnRH regulates both LH glycosylation and LH polypeptide synthesis and that E2 lowers the physiological concentration of GnRH necessary to stimulate this biosynthetic response.”
The effects of gonadotropin-releasing hormone and estradiol on luteinizing hormone biosynthesis in cultured rat anterior pituitary cells.“Stimulation of total cells or gonadotrophs by LHRH promoted the synthesis and release of a specific polypeptide (apparent molecular weight 87,000, pI = 4.6).”
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