supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Oxytocin
Research Papers that Mention the Interaction
“ GnRH caused a significant decrease in the maximal contraction intensity of nonpregnant and pregnant uterine muscle strip, following the action of oxytocin and acetylcholine.”
GnRH in pregnancy“Additionally the increased LH levels observed in the peripheral circulation of pentobarbitone-anaesthetised rats administered GnRH were enhanced if the rats received oxytocin prior to the GnRH.”
“Incubation of pituitary pieces with oxytocin plus GnRH induced secretion of amounts of LH greater than the sum of the amounts released by oxytocin and GnRH separately.”
“Thus oxytocin synergised with GnRH in stimulating LH release.”
“NE, GA and oxytocin stimulate LHRH release by activation of neural nitric oxide synthase (nNOS).”
“Using qRT-PCR, we found that oxytocin treatment increased Gnrh mRNA levels in both the PH and AH.”
Oxytocin Intranasal Administration Affects Neural Networks Upstream of GNRH Neurons“It has been delineated that oxytocin stimulates GnRH release from the rat hypothalamic explants and intranasal applied oxytocin up-regulates GnRH expression in the male rat hypothalamus.”
“Intracerebroventricular (icv) infusion (experiment in vivo) of a GnRH antagonist resulted in substantial inhibition of OT release, thus revealing the stimulatory action of endogenous GnRH.”
“The results show that the highly selective GnRH agonist (i.e., [Des-Gly(10),d-His(Bzl)(6),Pro-NHEt(9)]-LHRH; Histrelin) stimulates the secretion of OT from an isolated rat H-N system.”
“The administration of an oxytocin antagonist for 6 d to immature female rats decreased GnRH pulse frequency ex vivo and delayed the age at vaginal opening and first estrus.”
“Together, these data suggest that oxytocin may directly control neuronal activity in a subpopulation of GnRH neurones.”
“Recent studies from our laboratory have demonstrated that oxytocin induces dose‐dependent release of GnRH from proestrous basal hypothalamus explants.”
“The ability of OT (10–15–10–9M) to stimulate the release of GnRH was determined in both ME and BH explants on PE and DI.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback