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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Glycyrrhetinic Acid
supplement:
Tretinoin
Research Papers that Mention the Interaction
“Therefore, GA , the active metabolite of GL, as a novel AKR1B10 inhibitor, could promote retinoic acid synthesis.”
Glycyrrhetinic acid attenuates disturbed vitamin a metabolism in non-alcoholic fatty liver disease through AKR1B10.“In combined treatment with 5.0 μmol/L RA and 25 μmol/L GA , the inhibition of invasion was greater than the sum of them used alone.”
“RESULTS Treated with RA an d GA, t he proliferation of PGCL3 cells were inhibited obviously, and the inhibition degree was related to the dosage of the drugs.”
“Treated with GA of above concentation, the colony formation rate in semi-solid agar was decreased significantly (P < 0.001).. CONCLUSIONS RA and GA can inhibit the proliferation and invasion of the PGCL3 human lung cancer cells and have the anti-invasion synergism.”
“Treated with GA of above concentrations and 10 μmol/L RA , the adhesion and migration ability and the secretion of CB of the PGCL3 cells were decreased significantly (P < 0.001).”
[Studies on proliferation inhibition and anti-invasion of retinoic acid and 18β-glycyrrhetinic acid in highly metastasized human lung cancer cell line].
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