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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Glycylglycine and Morphine

supplement:

Glycylglycine

Research Papers that Mention the Interaction

In this study, we tested the hypothesis that Gly-Gln inhibits morphine reward by blocking morphine-induced dopamine efflux in the nucleus accumbens (NAc).
These data support the hypothesis that Gly-Gln abolishes the rewarding effect of morphine by inhibiting the ability of morphine to stimulate dopamine release in the NAc.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2010  |  View Paper
Previously, we showed that Gly-Gln inhibits morphine conditioned place preference, tolerance, dependence and withdrawal.
European journal of pharmacology  •  2006  |  View Paper
Glycyl-glutamine inhibited the development of morphine dependence when given to rats twice daily immediately before they received morphine (10 mg/kg i.p.)
Journal of Pharmacology and Experimental Therapeutics  •  2005  |  View Paper