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“The CRDs of DC-SIGN and DC-SIGNR bind Man9GlcNAc2 oligosaccharide 130- and 17-fold more tightly than mannose, and affinity for a glycopeptide bearing two such oligosaccharides is increased by a further factor of 5- to 25-fold.”
The Journal of biological chemistry • 1979 | View Paper
“The peptide backbone of the glycopeptide also affects the PHA-inhibitory activity of the oligosaccharide chain since higher molecular weight glycopeptides extracted from erythrocyte membranes with chloroform-methanol lose 90% of their PHA-inhibitory activity following proteolytic digestion with trypsin.”