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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glycine
drug:
Tranexamic Acid
Research Papers that Mention the Interaction
“… TXA increases … inhibits neural glycine receptors.6,7 When one examines the chemical structures of TXA, γ-aminobutyric acid, and glycine and their similarities, additional mechanisms may … agent, has not been reported to produce seizures.5 Lecker et al.1 report that high concentrations of TXA inhibit NMDA receptors.”
Understanding Potential Drug Side Effects: Can We Translate Molecular Mechanisms to Clinical Applications?“Conclusions: Tranexamic acid inhibits NMDA receptors likely by reducing the binding of the co-agonist glycine and also inhibits &agr;-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and kainate receptors.”
High Concentrations of Tranexamic Acid Inhibit Ionotropic Glutamate Receptors
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