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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glycine
drug:
Topiramate
Research Papers that Mention the Interaction
“However, in presence of 1 mM glycine + 1 mM TPM , the desensitization got faster and the peak current amplitude decreased.”
Interaction of topiramate with glycine receptor channels.“At high therapeutic concentrations, topiramate (in 24% of neurons) and pentobarbital reversibly decreased glycine currents to 89+/-6 % and 81+/-7 % of control, respectively.”
Effects of seven clinically important antiepileptic drugs on inhibitory glycine receptor currents in hippocampal neurons
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