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Last Updated: 2 months ago

Possible Interaction: Glycine and Threonine

supplement:

Glycine

supplement:

Threonine

Research Papers that Mention the Interaction

SummaryPreclinical data indicate that the administration of the amino acid L-threonine increases glycine levels in rat spinal cord.
Clinical neuropharmacology  •  1991  |  View Paper
The presented data indicate that increasing the threonine in plasma leads to increasing brain glycine and thereby affects the neurotransmitter balance in the brain.
There was a positive significant correlation between threonine and glycine concentrations in the cortex (r = 0.673, p < 0.01), and the brain stem (r = 0.575, p < 0.01), whereas the glycine concentration decreased with increasing threonine intakes in the liver and muscle.
Pediatric Research  •  1998  |  View Paper
Threonine conversion to glycine tended to be higher on + Thr and +P-Thr vs. control (3.5, 3.4, and 1.6 micromol x kg(-1) x h(-1), SD 1.3, P = 0.06).
American journal of physiology. Endocrinology and metabolism  •  2000  |  View Paper
The significant increase of the glycine and of glutaminic acid with threonine levels (36.4% and 62.2%, respectively) and significant decrease in the level of leucine with isoleucine (16.5%) has been stated in patients if compare with the control group.
Przeglad lekarski  •  1990  |  View Paper
At d 35, an interaction (P ≤ 0.01) … observed between the Gly+Ser and dig Thr levels for G:F. Glycine supplementation resulted in a linear increase (P < 0.05) in BW gain, G:F, intestinal mucin secretion, apparent digestibility of fat, and AME values of the experimental diets.
Poultry science  •  2013  |  View Paper
Further analysis indicated that glycine uptake was independent of luminal pH and proline, but a component of uptake was significantly impaired by 100-fold excesses of threonine or asparagine.
Journal of Comparative Physiology B  •  2011  |  View Paper
Added glycine (0.3 mM) marginally suppressed threonine oxidation.
American journal of physiology. Endocrinology and metabolism  •  2001  |  View Paper
Whole-body glycine , proline, serine and cystine concentrations decreased (P < 0.05) as Thr was increased in the diet.
The British journal of nutrition  •  1997  |  View Paper
Simultaneously there is a significant increase of glycine and threonine in plasma.
Infusionstherapie und klinische Ernahrung  •  1987  |  View Paper
In intact and freeze-thawed mitochondria, the ratio of glycine to aminoacetone formed was markedly sensitive to the concentration of L-threonine , glycine being the major product at low L-threonine concentrations.
Biochimica et biophysica acta  •  1984  |  View Paper
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