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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Glycine and Spermine

supplement:

Glycine

Research Papers that Mention the Interaction

Using this assay, spermine and spermidine increased both the affinity and the maximum effect of glycine.
Neuropharmacology  •  1995  |  View Paper
Enhancement curves by glycine in the presence of increasing concentrations of the glycine antagonist 7-chlorokynurenate revealed that spermine markedly increased the affinity of glycine but not that of 7-chlorokynurenate, and that glycine was also required for [3H]dizocilpine binding in the presence of spermine.
European journal of pharmacology  •  1994  |  View Paper
Spermine increased the affinity of glycine site agonists in displacing [3H]L-689,560 binding, with no effect on inhibition by partial agonists or antagonists, suggesting that spermine promotes an 'agonist-preferring' state.
European journal of pharmacology  •  1994  |  View Paper
Dose‐response analysis for the glycine‐sensitive activation of NMDA receptors at +60 mV revealed a 3.5‐fold increase in apparent affinity for glycine in the presence of 1 mM spermine.
The Journal of physiology  •  1993  |  View Paper
Spermine was inhibitory for growth of L phase induced by glycine.
Infection and immunity  •  1970  |  View Paper