Possible Interaction: Glycine and Proline

“An inhibitor of l-proline uptake, glycine , prevented the differentiation of ES cells in response to MEDII.”

“Compared with the essentials, both glycine and proline had significantly lower F/M enrichment ratios, which were not different from each other.”

“Substitution of Gly with l-Pro switched the receptor preference of the peptides from CXCR4 to CXCR7.”

“Figure 1 A shows the conformations adopted by glycine residues in our dataset, and the …, centred around y= 08 and y= 1808, is clearly evident in Figure 1 B. Proline severely restricts the conformational freedom … C, D), particularly that of glycine : whereas 34.9 % (9196 … glycines in Figure 1.”

“The exchange of the glycine residue by prolin in compounds former described caused a decreased antithrombin effect.”

“The GLY 3 peak interfered with the resolution of TMS leucine and TMs proline due to the large quantity of glycine in the sample.”

“Substitution of the glycine 531 residue by a proline selectively reduced the hemolytic capacity but did not affect the AC translocating activity of the CyaA-G531P toxin.”

“ Glycine , l-alanine, and l-tryptophan strongly inhibited l-proline uptake indicating that these amino acids also interact with the transport system.”

“Counterflow accumulation of proline was elicited by glycine and vice versa, suggesting that the two amino acids are transported by a common symporter, which we designate the pro, gly: K+ symporter.”

“ Glycine , lysine, arginine, valine, isoleucine, and tryptophan in the second position are (with N-terminal serine) strongly inhibitory, and proline completely blocks modification.”