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Last Updated: a year ago

Possible Interaction: Glycine and Phenylalanine





Research Papers that Mention the Interaction

The biomarkers described by the authors demonstrate a potential causal connection between changes in glycine and phenylalanine and incident diabetes mellitus.
Nature Reviews Endocrinology  •  2018  |  View Paper
Substitution of the C-terminal penultimate glycine and proline residues of prooxytocin and procalcitonin and their analogues with phenylalanine increases the enzyme binding affinity.
Bioorganic & medicinal chemistry letters  •  2012  |  View Paper
glycine (calculated from that of … oral administration of l-phenylalanine , and of ammonium citrate, deviate from theory not only in the early stages of excretion, but in the attainment of … indicates the possibility that the turnover rate of glycine is higher than the average for ammonia-forming amino acids.
Journal of applied physiology  •  1959  |  View Paper
A high extracellular concentration of glycine prevented the attenuation by L‐Phe of NMDAR current, activated by exogenous agonist, and of NMDAR s/mEPSC amplitude, but not of NMDAR s/mEPSC frequency.
Journal of neuroscience research  •  2003  |  View Paper
Site-directed mutagenesis of the gamma-aminobutyric acid type A (GABA(…)) receptor beta(2) subunit has demonstrated that conversion of a conserved glycine residue located at the entrance to the first transmembrane domain into the homologous rho(1) residue phenylalanine alters the modulating effects of four different i.v.
Molecular pharmacology  •  2000  |  View Paper
The pairing of glycine and phenylalanine across antiparallel strands resulted in a synergistic increase in protein stability.
Folding & design  •  1998  |  View Paper
In vesicles … of glycine was … and L-phenylalanine , whereas addition of L-proline to the incubation medium did not significantly alter the uptake of glycine, suggesting that the Na(+)-… in pars recta is shared with the high-affinity L-alanine and L-phenylalanine but not L-proline transport system.
The American journal of physiology  •  1990  |  View Paper
Replacement of phenylalanine-7 by glycine resulted in a large decrease in potency in both bioassays, illustrating the importance of the side chain group, in this position of alpha-MSH, to biological potency of the hormone.
International journal of peptide and protein research  •  1986  |  View Paper
Although the hepatic accumulation of L-phenylalanine was not stimulated by γ irradiation, it effectively inhibited the stimulated transport of AIB, methionine, cycloleucine, and glycine.
Radiation research  •  1978  |  View Paper
The lecithin-dependent change in the selectivity shown between glycine and phenylalanine is suggested as being brought about by entropic effects in the hydrocarbon core of the phospholipid bilayer.
Biochimica et biophysica acta  •  1971  |  View Paper
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