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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glycine
drug:
Pentobarbital
Research Papers that Mention the Interaction
“2) Pentobarbital and thiopental potentiate the current response to bath applied glycine (50 microM) by 200 and 300%, respectively, at clinically relevant concentrations. (”
Post-synaptic inhibitory mechanisms of anaesthesia; glycine receptors.“Currents elicited by 0.03 mM glycine were enhanced by pentobarbital showing potentiation of alpha(1)beta glycine receptor channels.”
“The cardiovascular response to GABA, but not to glycine , was potentiated by pretreatment with pentobarbitone (50 mg/kg i.p.).”
Cardiovascular effects of intracerebroventricular GABA, glycine and muscimol in the rat“At high therapeutic concentrations, topiramate (in 24% of neurons) and pentobarbital reversibly decreased glycine currents to 89+/-6 % and 81+/-7 % of control, respectively.”
“Co-application of 0.3 mm PB reduced the peak amplitude, affected the macroscopic desensitization and deactivation of the response to externally applied Gly in a concentration-dependent manner.”
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