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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Glycine and Papain

supplement:

Glycine

supplement:

Papain

Research Papers that Mention the Interaction

Substitution of the two deduced contact …, Leu-73 and His-75, with Gly resulted … papain and cathepsins H and B. These losses indicated that the two residues together contribute 20-30% of … of cystatin B to these enzymes and that Leu-73 is responsible for most of this contribution.
Biochemistry  •  1999  |  View Paper
Substitution of this residue by Gly markedly altered the spectroscopic changes accompanying papain binding and reduced the affinity for papain, actinidin, and cathepsins B and H by 300-900-fold.
Biochemistry  •  1996  |  View Paper
Gly‐9 and Ala‐… for papain than the two isoelectric forms (pI=6.5 and 5.6) of the full‐length inhibitor (K i=6 pM and 7 … Leu‐7 (K i=6 pM), indicating the outstanding importance of one or two residues preceding conserved Gly‐9 for binding.
FEBS letters  •  1989  |  View Paper