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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Glycine
drug:
Norepinephrine
Research Papers that Mention the Interaction
“Both GLY –DEX and TMP infusion inhibited norepinephrine release (P<0.01 vs control).”
Autonomic Cardiovascular Control During a Novel Pharmacologic Alternative to Ganglionic Blockade“IT noradrenaline decreased the levels of glycine and gamma-aminobutyric acid (GABA) in the lumbosacral cord, while IT naftopidil increased the GABA level.”
Spinal mechanism of micturition reflex inhibition by naftopidil in rats.“ NE reversibly and concentration dependently facilitated Cl(-) current induced by 3 x 10(-5) M glycine.”
“These opposing effects on inhibitory synaptic strength are mediated presynaptically where 5‐HT decreases and NA increases the probability of glycine release from inhibitory terminals.”
“Some noradrenaline uptake inhibiting ADS (desipramine and viloxazine, but not maprotiline) were also significantly more effective in decreasing immobility time when combined with GLY than when administered alone.”
“ Glycine (1 microM) also increased NA release evoked by NMDA.”
“ Glycine caused a concentration-dependent evoked release of [3H]norepinephrine from rat hippocampal brain slices.”
“In this article, glycine is shown to increase the Ca2+‐dependent release of [3H]norepinephrine from preloaded slices of the rat hippocampus.”
“ NE was found to preferentially augment GABA-induced inhibition, whereas it antagonized inhibition produced by glycine.”
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