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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glycine
Research Papers that Mention the Interaction
“In the spinal motoneurone of newborn rats, glycine (100 microM-1 mM) induced depolarizing responses in a concentration-dependent manner.”
“ Glycine (5-10 mM) completely eliminated the depolarizing response of the C-cell, whereas the hyperpolarizing component was unaffected.”
A chromatic horizontal cell in the Xenopus retina: intracellular staining and synaptic pharmacology.“While the effect of glycine in slices was increased by decreasing the depolarizing concentration of K+ (about 500% potentiation at 9 mM K+), the response of synaptosomes remained minimal, even in presence of 9 mM KCl.”
“…,depolarizing agents induce the calcium-dependent release of physiologically active compounds, including acetylcholine (de Belleroche &Bradford, 19726), …-aminobutyrate (de Belleroche & Bradford, 1972a) and noradrenaline (Blaustein et al., 1972) from cerebral cortex, glycine , aspartate and y-aminobutyrate from spinal cord (Osborne et …), and releasingfractors from hypothalamus (Edwardson et al., 1972).”
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