“We found that 33 urinary metabolites were significantly changed in DM compared with CM, and … 16 metabolites among them, namely, glucose, mannose, myo-inositol, pyruvate, fumarate, 2-hydroxyglutarate, isobutyrate, glycine , threonine, dimethylglycine, methyldantoin, isoleucine, leucine, acetylcarnitine, 3-hydroxy-3-…, shifted closer to the control level in response to losartan ….”