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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Glycine and Lidocaine



Research Papers that Mention the Interaction

CONCLUSIONS Lidocaine and procaine enhanced glycine receptor function at low concentrations and inhibited the functions of glycine and GABAA receptors at high concentrations.
Anesthesia and analgesia  •  2007  |  View Paper
Inhibition of glycine uptake by a combination of lidocaine with its metabolites at a clinically relevant concentration was diminished with increasing extracellular glycine concentrations.
Results: Lidocaine reduced glycine uptake only at toxic concentrations.
Anesthesiology  •  2012  |  View Paper
A combined injection of GABA agonist or glycine with lidocaine (0.5%) prevented the inhibitory effects of lidocaine injection alone.
PAIN®  •  2010  |  View Paper