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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“CONCLUSIONS Lidocaine and procaine enhanced glycine receptor function at low concentrations and inhibited the functions of glycine and GABAA receptors at high concentrations.”
The Effects of the Local Anesthetics Lidocaine and Procaine on Glycine and &ggr;-Aminobutyric Acid Receptors Expressed in Xenopus Oocytes“Inhibition of glycine uptake by a combination of lidocaine with its metabolites at a clinically relevant concentration was diminished with increasing extracellular glycine concentrations.”
“Results: Lidocaine reduced glycine uptake only at toxic concentrations.”
Lidocaine Metabolites Inhibit Glycine Transporter 1: A Novel Mechanism for the Analgesic Action of Systemic Lidocaine?“A combined injection of GABA agonist or glycine with lidocaine (0.5%) prevented the inhibitory effects of lidocaine injection alone.”
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