Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Glycine and Isoleucine

supplement:

Glycine

supplement:

Isoleucine

Research Papers that Mention the Interaction

RESULTS:Mutation of the α1 subunit TM2 serine residue to either isoleucine or methionine decreased the sensitivity of the receptor to glycine , and abolished the direct activation of the glycine receptor by propofol.
Anesthesia and analgesia  •  2008  |  View Paper
Via alanine, isoleucine , L-serine dehydratase/L-threonine deaminase and other proteins, AgNP-cit altered the metabolism of glycine , serine and threonine, cysteine and methionine, affecting oxidation and deamination, and ultimately leading to liver damage.
Nanotoxicology  •  2018  |  View Paper
While the G189A mutant was able to complement CMP-sialic acid transport-deficient Chinese hamster ovary mutants, the exchange of glycine 189 into glutamine or isoleucine dramatically affected the transport activity of the CMP-sialic acid transporter.
The Journal of Biological Chemistry  •  1998  |  View Paper
Phenylalanine and tyrosine inhibit one site; proline and the straight-chain amino acids, alanine, methionine and cysteine inhibit another; and glycine and the branched-chain valine, leucine, and isoleucine inhibit a 3rd.
The Journal of protozoology  •  1970  |  View Paper
Valinomycin treatment was found to stimulate the rate of lysine uptake until equilibrium had been achieved; whereas the characteristics of glutamate uptake were unaffected, a transient stimulation of glycine and isoleucine uptake was found to occur.
FEBS letters  •  1973  |  View Paper