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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glycine
drug:
Interleukin-10
Research Papers that Mention the Interaction
“ GLY decreased LPS‐induced TNF‐α production (P<0.01) and increased IL‐10 expression of purified monocytes.”
“Similarly, in a whole blood assay, GLY reduced TNF‐α (P< 0.0001) and IL‐1β (P<0.0001) synthesis and increased IL‐10 expression (P<0.05) in a dose‐dependent manner.”
Immunomodulatory effects of glycine on LPS‐treated monocytes: reduced TNF‐α production and accelerated IL‐10 expression“Furthermore, Gly inhibited colonic gene expression of interleukin- (IL-) 1β and promoted IL-10 expression in colitis mice.”
The Effects of Dietary Glycine on the Acetic Acid-Induced Mouse Model of Colitis“Further research revealed that GLY exposure also promoted expression of NF-κB, iNOS, IL-1β, IL-6, IL-8, and TNF-α; altered the levels of IL-10 and TGF-β, indicating that GLY exposure induced inflammatory response in the fish gills.”
“However, the mRNA levels of adiponectin and interleukin-10 (IL-10), two adipose-derived adipocytokines with anti-inflammatory effects, were greatly enhanced (P < 0.05) by 2 mmol/L glycine.”
“In conclusion, glycine exposure enhanced the mRNA levels of adipose-derived adiponectin and IL-10 without affecting adipogenesis and lipolysis in 3T3-L1 adipocytes.”
“The early systemic increase of the proinflammatory cytokines tumor necrosis factor-alpha (TNF-alpha) and interleukin (IL) -6 as well as the secretion of the antiinflammatory cytokine IL-10 was reduced by glycine.”
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