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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Indole and skatole, as well as tribromethanol, choretone and pentothal, inhibit the uptake of glycine into Ehrlich ascites cells under anaerobic conditions in presence of glucose, the extent of ihibition being greater than the inhibition of anaerobic glycolysis.”
Effects of lipotropic agents on the metabolism of Ehrlich ascites carcinoma cells and other tissues.“Chlorine, and other small electron-withdrawing …- and 6-positions of the indole ring , greatly enhanced … the glycine site over the glutamate site of the NMDA receptor; one of the most potent compounds is 3-(…-carboxyindol-3-yl)propionic acid (IC50 = 170 nM; greater than 2100-fold selective for glycine).”
3-(2-Carboxyindol-3-yl)propionic acid-based antagonists of the N-methyl-D-aspartic acid receptor associated glycine binding site.“ Indole decreases the absorbance obtainable at 500 … hydrophobic side chains (L-Ala, Gly ), increases this absorbance for amino acids with small polar side chains (beta-cyano-L-alanine), and does not … with amino acids with bulky side chains, i.e. amino acids whose binding affinities are unaffected by indole.”
Some effects of indole on the interaction of amino acids with tryptophanase.
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