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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glycine
Research Papers that Mention the Interaction
“Maximal amplitude currents resulted when glutamate-site agonists were combined with either glycine or D-serine; both of these amino acids were, therefore, defined as full agonists at the glycine site.”
Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells.“In fact, REM atonia persists even when glycine and GABAA receptors are blocked and potent glutamatergic agonists are simultaneously applied to the trigeminal motor pool.”
Unraveling the mechanisms of REM sleep atonia.“We have also measured the affinities and intrinsic activities of several NMDA receptor ligands and report that a reciprocal interaction exists, such that the off-rate of glycine is influenced by the properties of the agonist occupying the glutamate coagonist site.”
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