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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glycine
drug:
Deoxycholate
Research Papers that Mention the Interaction
“Incubation of Kupffer cells with DCA led to increased intracellular calcium that could be blocked by incubation with glycine.”
“Incubation of isolated hepatocytes with DCA led to a significant release of LDH after 4 h. This release was largely blocked when incubation with glycine was performed.”
Dietary glycine blunts liver injury after bile duct ligation in rats.“These studies suggested that deoxycholic acid is 7 alpha-hydroxylated after amidation with glycine or taurine in vivo and that the same enzyme may well catalyze the 7 alpha-hydroxylation of glycodeoxycholate and taurodeoxycholate in the hamster.(ABSTRACT TRUNCATED AT 250 WORDS)”
“ Deoxycholate at 8 microM in the blood supply of the perfused jejunal segment was associated with a significant (p less than 0.02) reduction in the absorption rates of water, sodium, glucose, and glycine , and inhibition of mucosal Na+, K+-ATPase.”
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