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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Glycine and Chenodeoxycholate

supplement:

Glycine

Research Papers that Mention the Interaction

Deconjugation and 7 alpha-dehydroxylation of mixtures of glycine- or taurine-conjugated cholate and chenodeoxycholate drastically increased their cytotoxicity.
The American journal of physiology  •  1991  |  View Paper
Conjugation of either lithocholate or chenodeoxycholate with either glycine or taurine markedly reduced the ability of the bile salt to enhance O2- release from primed PMNs.
Toxicology and applied pharmacology  •  1988  |  View Paper
Conjugation … chenodeoxycholate with glycine , epimerization of chenodeoxycholate from 7 alpha-hydroxy to 7 beta-hydroxy as in ursodeoxycholate, or addition of a third hydroxyl group as in cholate all eliminated the increase in jejunal HRP penetration and led to HRP absorption levels like those in bile salt-free preparations.
The American journal of physiology  •  1983  |  View Paper