Possible Interaction: Glycine and Calcium Supplement

“Previously, it was shown that glycine prevented increases in intracellular calcium ([Ca2+]i) in Kupffer cells.”

“The carbonyl groups of glycine and valine have long bond lengths, consequently generating potent affinities to divalent cations such as calcium.”

“Secondary chemical bonding between calcium and carbonyl oxygen atoms of glycine and valine might give rise to aggregates in the brain, which may later result in cell senescence.”

“The addition of 50 mmol/l glycine base to the HEPES-buffered media increases the thrombin-induced entry of calcium or manganese.”

“ Glycine most likely prevents the LPS-induced elevation of intracellular Ca concentration in Kupffer cells, thereby minimizing LPS receptor signaling and cytokine production.”

“Seven amino acids glycine , l-isoleucine, l-phenylalanine, l-proline, l-serine, l-threonine, and l-tryptophan) and five organic acids (benzoic acid, citric acid, fumaric acid, SA, and succinic acid) increased in ' Ca.”

“In the present study, ducks fed mycotoxin-contaminated corn decreased nutrient digestibility in dose-dependent manner, and 0.1% CA supplementation improved AD and TD of Gly and Pro.”

“Incubation of Kupffer cells with DCA led to increased intracellular calcium that could be blocked by incubation with glycine.”

“The synaptic output of about two‐thirds of bipolar cells and calcium current in two‐thirds of ganglion cells are sensitive to the action of glycine at metabotropic receptors, suggesting this signal regulates specific synaptic pathways in proximal retina.”

“Evoked glycine release was 50% reduced when calcium was omitted from the medium.”