Possible Interaction: Glycerol and Xylitol

“Addition of 10 mM sorbitol, xylitol , or ethanol to the hepatocytes increased glucose production from pyruvate 25-40%, while glycerol addition increased it only 9%.”

“Hence, joint application of glycerol and xylitol may be a useful therapeutic approach for different skin disorders.”

“The amount of glycerol consumed per amount of xylitol produced (0.47 mol mol−1) was significantly lower than glucose (23.7 mol mol−1).”

“XYL1 overexpressed mutant grown on glycerol as co-substrate accumulated 2.1-fold increased xylitol concentration over those cells grown on glucose as co-substrate.”

“ZUC99(pATX210) produced 2.6 g/l xylitol using 4.2 g/l L-arabinose with a xylitol yield of 0.62 g/g L-arabinose in 36 h. It was determined that utilization of glycerol as a co-substrate significantly improved xylitol production and yield.”

“According to the results, the addition of 0.7 g/l glycerol to the fermentation medium favored not only the yield (YP/S = 0.78 g/g) but also the xylitol productivity (QP = 1.13 g/l/h).”

“Glycerol surprisingly did not inhibit the uptake of xylitol, and xylitol only slightly reduced the uptake of glycerol.”