Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Glycerol and Vitamin B 12

supplement:

Glycerol

supplement:

Vitamin B 12

Research Papers that Mention the Interaction

Growth of these strains on minimal media supplemented with glycerol as a carbon source resulted in significant increases in cobalamin production (up to 200 μg L(-1)).
New biotechnology  •  2014  |  View Paper
Glycerol stabilizes cyanocob(III)alamin (vitamin B12) against anaerobic photolysis by a high-intensity UV light source or a low-intensity fluorescent light source.
Journal of pharmaceutical sciences  •  1993  |  View Paper
The diol dehydratase was inhibited by various corrinoids (adenosylcobalamin, cyanocobalamin , hydroxocobalamin, and methylcobalamin) by up to 37% at a concentration of 100 muM. Changes in ionic strength and the K ion concentration had only limited effects on this enzyme activity; glycerol inhibited the enzyme by 95%.
The diol dehydratase was inhibited by various corrinoids (adenosylcobalamin, cyanocobalamin , hydroxocobalamin, and methylcobalamin) by up to 37% at a concentration of 100 μM. Changes in ionic strength and the K+ ion concentration had only limited effects on this enzyme activity; glycerol inhibited the enzyme by 95%.
Applied and environmental microbiology  •  1992  |  View Paper