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Last Updated: 3 years ago

Possible Interaction: Glycerol and Sorbinil

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supplement:

Glycerol

drug:

Sorbinil

Research Papers that Mention the Interaction

“ Sorbinil , a classical ALR2 inhibitor, present in the enzyme assay mixture, inhibits to the same extent both NADPH oxidation and glycerol formation.”

Aldose reductase does catalyse the reduction of glyceraldehyde through a stoichiometric oxidation of NADPH.

Experimental eye research • 2000 | View Paper

“ Sorbinil treatment (40 mg/kg) decreased the lens content of sorbitol to 0.60 ± 0.06, fructose to 0.85 ± 0.08, and glycerol 3-phosphate to 0.36 ± 0.03 μmol/g; glucose 6-phosphate remained unchanged.”

The Effect of an Aldose Reductase Inhibitor (Sorbinil) on the Level of Metabolites in Lenses of Diabetic Rats

Diabetes • 1983 | View Paper

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