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Last Updated: 4 months ago

Possible Interaction: Glycerol and Pulmonary Surfactants

Research Papers that Mention the Interaction

As co-surfactant, glycerol may intercalate within the polyoxyethylene chains of the surfactant at the palisade layer, increasing the interface flexibility and expanding it.
AAPS PharmSciTech  •  2017  |  View Paper
The addition of glycerol or PEG to the surfactant solutions had only a minor impact on the solubility.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences  •  2006  |  View Paper
For Brij 58, in spite of the lowering of the aggregation number, the surfactant intradiffusion coefficient decreases with increasing glycerol concentration, suggesting an increase of the intermicellar interaction.
In the case of Brij 58, the results can be interpreted in terms of a salting-out effect according to which glycerol competes with the surfactant for water molecules, causing a dehydration of the surfactant ethoxylic headgroup.
Journal of colloid and interface science  •  2005  |  View Paper
We found that glycerol increases the aggregation number and withdraws the hydrating agents from the headgroup region of the surfactant , resulting in a higher packing density of molecules in a micelle at slightly increasing size.
Journal of colloid and interface science  •  2004  |  View Paper
Evidence is presented for the detection of distonic radical cations of the surfactant , complexed (solvated) with glycerol.
Journal of the American Society for Mass Spectrometry  •  1992  |  View Paper