Possible Interaction: Glycerol and Potassium Chloride

“We identified a significant correlation between the ability to survive in glycerol and the ability to survive in KCl and biofilm formation, which may be important for food safety and the protection of public health.”

“Zn2+ was found to inhibit the activity of GBV‐B NS5B, with a 50% inhibitory concentration (IC50) of 5–10 μM. Higher concentrations of monovalent salts (NaCl or KCl > 100 m M) and glycerol (> 3%) were also inhibitory.”

“The positive inotropic effects of tyramine, dimethylphenylpiperazinium and potassium chloride were decreased showing an inhibition of noradrenaline liberation induced by glycerol formal at the doses used.”

“ Glycerol exposure elicited the downregulation of these osmoadaptive mechanisms but stimulated an increase in lipopolysaccharide and membrane protein-associated genes after 1 h. The most extensive changes in gene expression occurred following exposure to KCl.”

“The interaction was not inhibited by either 0.1 M KCl or 0.4 M (NH4)2SO4, but was completely prevented by 5% glycerol.”

“Other osmoregulatory solutes such as sucrose and glycerol also reduced KCl inhibition, though to a lesser extent than betaine.”

“Reduction of a(w) with glycerol was less inhibitory to growth than similar a(w) reductions with NaCl and KCl.”

“ Glycerol does not activate the enzyme, but increases its activity in the presence of potassium chloride.”