Possible Interaction: Glycerol and Norepinephrine

“Theophylline and norepinephrine alone increased glycerol outflow significantly.”

“ Noradrenaline produced a significant rise in the level of cAMP and significantly stimulated the rate of glycerol production.”

“ Norepinephrine and norfenefrine induced a four and three fold rise in glycerol dialysate concentration (p<0.001, each), with a similar pattern in adipose tissue.”

“Functionality of our 3-D single-layer hypodermis was demonstrated both by a 3.5-fold glycerol production after its stimulation with norepinephrine (adrenergic agonist) and by its slimming after caffeine treatment versus the nontreated 3-D hypodermis.”

“In subcutaneous adipose tissue, microdialysis experiments revealed a higher and prolonged glycerol release in the presence of norepinephrine , but not under basal conditions.”

“Basal lipolysis was significantly reduced and noradrenaline significantly increased both glycerol release and cAMP production.”

“Changes in the ratio of glycerol to noradrenaline (Gly/Nad), as an index of lipolytic efficiency, were significantly high at C as compared with WH (p<0.01).”

“ Norepinephrine induced adipocyte lipolysis and circulating fasting levels of free fatty acids and glycerol were reduced by half in TT carriers.”

“ Noradrenaline increased the net release of glycerol by adipose tissue three-fold and that of non-esterified fatty acids three- to four-fold.”

“Before starvation adrenaline and noradrenaline caused a 2–3‐fold increase of glycerol release.”