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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Concentrations of plasma free fatty acids (FFA) and glycerol were suppressed following NA ingestion irrespective of preexercise nutritional intake but were higher throughout exercise in FAST compared with all other trials (P < 0.05).”
Altering fatty acid availability does not impair prolonged, continuous running to fatigue: evidence for carbohydrate dependence.“ Serum glycerol levels were also significantly lower during exercise in the nicotinic acid trial , indicative of a reduction in lipolysis.”
“After 86 h of fasting, nicotinic acid decreased glycerol Ra and hence lipolytic rate by approximately 60%.”
“Despite the higher insulin concentrations, circulating levels of NEFA, ketone bodies, and glycerol were all significantly elevated during treatment with nicotinic acid.”
“High diffusivity induced by the hydration effect of glycerin and water could be the major contributing factor for the enhanced skin permeation of nicotinic acid (NA).”
Gravimetric analysis and differential scanning calorimetric studies on glycerin-induced skin hydration“Insulin (100 …) and nicotinic acid (0.1 μM) … AMP accumulation and glycerol production induced by ADA.The results support the hypothesis that adenosine is released from isolated fat cells and that … may serve as an inhibitor of adenyl cyclase activity, thus regulating cyclic AMP-dependent processes in adipose tissue.”
“ Glycerol formal upon a perfusion at 11 mmol/l/h decreased mildly the positive inotropic effect of noradrenaline, and strongly that produced by acetylcholine at a nicotinic dose , while it accentuated the bradycardia induced by acetylcholine at a muscarinic dose.”
“2 Although the changes were not statistically significant, the basal release of free fatty acid (FFA) was increased and glycerol was decreased by nicotinic acid (0.01–1 mm); the drug caused a statistically significant increase in basal FFA: glycerol ratio in a concentration‐dependent manner.”
“ Nicotinic acid (10(-5) M) prevented glycerol outflow during hypoxia but did not influence the outflow of noradrenaline during either hypoxia or reoxygenation.”
“Two antilipolytic drugs nicotinic acid and 3,5-dimethylpyrazole) blocked the elevation in plasma glycerol while having no effect on food intake.”
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