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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Insulin infusion also inhibited the expected rise in glycerol and 3-hydroxybutyrate normally observed during exercise.”
Effects of mild hyperinsulinemia on the metabolic response to exercise.“Both insulin and XMetA lowered β‐hydroxybutyrate levels in plasma; however, only insulin reduced both non‐esterified fatty acids (NEFA) and glycerol concentrations.”
“Results:Low-dose insulin infusion resulted in suppression of the glycerol rate of appearance ranging from 4% (most resistant) to 85% (most sensitive), indicating a good range of adipose tissue insulin sensitivity in the study population.”
“The … insulin … ( glycerol reduction, abd (%): UBO 40.4 (−14 to 66), LBO 46.0 (−8 to 66), lean 66.2 (2–78), ANOVA, P < 0.05), … groups (glycerol reduction, fem (%): UBO 44.4 (35–67), LBO 44.4 (0–63), lean 65.0 (43–79), ANOVA, P < 0.05).”
“The presence of insulin lowered glycerol uptake and corresponding fluxes involved in lipid metabolism for all glucose levels but otherwise exerted negligible effect on metabolism.”
“ Glycerol fluxes were similar between the two obese groups yet occurred in the face of different concentrations of insulin.”
“Thus, it is likely that free fatty acids (FFA), glycerol and other adipocytokines released from the ip adipose tissue may have peculiar effects on hepatic metabolism of glucose, triglycerides, insulin , and other substrates and hormones.”
“The fractional release of glycerol (difference between interstitial glycerol and arterialized venous plasma glycerol) was reduced by more than one-half in adipose tissue (P < 0.0001) in response to insulin , whereas it remained unaltered in skeletal muscle.”
“LR was appropriately low for body fat mass in LW, with a brisk increase between 0 and 1.5 h. A negative correlation exists between GR (abdominal area) and insulin levels in the postabsorptive state (P < 0.0001).”
“Net renal (0.3 +/- 0.1 v 0.1 +/- 0.1) ….3 v 0.4 +/- 0.2 micromol/kg x min) glycerol uptake … after insulin and increased (P < .05) with saline infusion (0.4 +/- 0.1 v0.….0 +/- 0.5 v1.8 +/- 0.4 micromol/kg x min, respectively).”
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