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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Glyburide
supplement:
Sphingosine 1-Phosphate
Research Papers that Mention the Interaction
“Pharmcological antagonists of ABC transporters, glyburide and MK-571 attenuated endogenous S1P release.”
A novel method to quantify sphingosine 1-phosphate by immobilized metal affinity chromatography (IMAC).“Similar to the intact erythrocytes, the uptake of S1P into IOVs was inhibited by glyburide and vanadate but not by the other ABC transporter inhibitors.”
“The S1P release was reduced by an ABCA1 transporter inhibitor, glyburide , but not by a multidrug resistance-associated protein inhibitor, MK571, or a multidrug resistance protein inhibitor, cyclosporine A. Furthermore, we measured S1P transport activity using rat erythrocyte inside-out membrane vesicles (IOVs).”
Characterization of the ATP-dependent Sphingosine 1-Phosphate Transporter in Rat Erythrocytes*“ S1P release from astrocytes was inhibited by the treatment of the cells with glybenclamide or small interfering RNAs specific to ATP‐binding cassette transporter A1 (ABCA1).”
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