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Last Updated: 3 years ago

Possible Interaction: Glutathione and Zonisamide

supplement:

Glutathione

Research Papers that Mention the Interaction

In an interesting recently published study, Asanuma et al reported that zonisamide , which is used as an antiepileptic medication and a novel antiparkinsonian drug, significantly increases glutathione levels in astroglial cells.
Annals of neurology  •  2011  |  View Paper
Furthermore, zonisamide affects an increases in the levels of glutathione and manganese superoxide dismutase expression and, it ameliorates reduction in the number of dopaminergic neurons in mice treated with 6hydroxydopamine (6-OHDA).
Brain and nerve = Shinkei kenkyu no shinpo  •  2009  |  View Paper
Zonisamide has neuroprotective effects though inhibition of quinoprotein and increasing the levels of GSH and Mn SOD.
Rinsho shinkeigaku = Clinical neurology  •  2008  |  View Paper
ZNS increased the glutathione (GSH) level in the spinal motor neurons of CSM rats.
Scientific Reports  •  2020  |  View Paper