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“In an interesting recently published study, Asanuma et al reported that zonisamide , which is used as an antiepileptic medication and a novel antiparkinsonian drug, significantly increases glutathione levels in astroglial cells.”
“Furthermore, zonisamide affects an increases in the levels of glutathione and manganese superoxide dismutase expression and, it ameliorates reduction in the number of dopaminergic neurons in mice treated with 6hydroxydopamine (6-OHDA).”