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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
supplement:
Zinc Chloride
Research Papers that Mention the Interaction
“In all cell lines tested, decreases in cellular GSH content and GR activity as well as an increase in oxidized glutathione (GSSG) were found after incubation of cells with zinc chloride.”
Effects of zinc chloride on glutathione and glutathione synthesis rates in various lung cell lines“It is our hypothesis that up-regulation of neuroprotective effectors GSH , ERK and BDNF) may be related to the antidepressant properties of zinc , but this will require additional work to be confirmed.”
Involvement of glutathione, ERK1/2 phosphorylation and BDNF expression in the antidepressant-like effect of zinc in rats“ Zinc chloride inhibited 78.2% of ecto-phosphatase activity, with Ki of 0.35 mM. Such inhibition was reversed by incubation with cysteine and GSH , but not DTT, serine, and GSSG, showing that cysteine residues are important for enzymatic activity.”
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