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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Glutathione and Vorinostat

supplement:

Glutathione

drug:

Vorinostat

Research Papers that Mention the Interaction

“Likewise, SAHA induced GSH depletion specifically in cancerous cells.”
Suberoylanilide hydroxamic acid induces thioredoxin1‐mediated apoptosis in lung cancer cells via up‐regulation of miR‐129‐5p
Molecular carcinogenesis  •  2017  |  View Paper
“With respect to ROS and glutathione (GSH) levels, SAHA increased ROS levels, especially mitochondrial O(2)•- in HeLa cells and also induced GSH depletion.”
Suberoylanilide hydroxamic acid-induced HeLa cell death is closely correlated with oxidative stress and thioredoxin 1 levels.
International journal of oncology  •  2014  |  View Paper
“ SBHA increased ROS levels including O2•− and induced GSH depletion in HeLa cells.”
Suberoyl bishydroxamic acid-induced apoptosis in HeLa cells via ROS-independent, GSH-dependent manner
Molecular Biology Reports  •  2012  |  View Paper
“Furthermore, cells treated with SAHA revealed a decrease in intracellular reduced glutathione ( GSH ) contents.”
Chemosensitization of oral squamous cell carcinoma cells to cisplatin by histone deacetylase inhibitor, suberoylanilide hydroxamic acid.
International journal of oncology  •  2007  |  View Paper